If you plan on hiring a car in Tanzania and driving yourself to Mikumi be prepared in the event of a breakdown or accident. See the Tanzania main page on the recommendations for driving in developing countries.
DO NOT enter a national park without a FULL tank of petrol. You should also have an emergency jerry can with at least 20 liters of fuel and a full-sized spare tire in case you damage your tire in a remote area and need to drive through difficult terrain.
Other equipment to bring includes a tow rope, shovel, machete, torch flashlight, first aid kit and extra drinking water for unexpected delays.
Although it's very unlikely you will have any difficulties if you must change a flat tire in the park, be aware that lions and cheetahs are ambush hunters. Don't stray to far from the vehicle and keep the children inside at all times.
Tsetse flies: They are very abundant in Mikumi. They are somewhat similar to houseflies but sting. In more densely forested parts of the park, keep your windows closed. If one does get in, kill it immediately as they are quick to bite. Tsetse fly bites can potentially be harmful to humans as they are carriers of the sleeping sickness virus.
fees/permits
Park FeesA visitor's permit costs $20US per person and is valid for 24-hours from time of purchase. Be advised that non-residents are expected to pay the park entry fee in US dollars not Tanzanian Shillings. Visitors must enter before 4pm and exit before 7pm. Those staying in one of the park's lodging facilities must be back at camp by 7pm.